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Sequence-dependent persistence length of long DNA

Using a high-throughput genome mapping approach, we have obtained circa 50 million measurements of the extension of internal human DNA segments in a 41 nm × 41 nm nanochannel. The underlying DNA sequences, obtained by mapping to the reference human genome, are 2.5 to 393 kilobase pairs long and cont...

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Detalles Bibliográficos
Publicado en:Phys Rev Lett
Main Authors: Chuang, Hui-Min, Reifenberger, Jeffrey G., Cao, Han, Dorfman, Kevin D.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839665/
https://ncbi.nlm.nih.gov/pubmed/29286779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevLett.119.227802
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