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HMGA2 enhances 5-fluorouracil chemoresistance in colorectal cancer via the Dvl2/Wnt pathway

Drug resistance is one of the main hurdles to overcome for the improvement of cancer patient survival. However, the underlying mechanisms remain largely unknown, and therapeutic options are limited. Here, we demonstrate a strong correlation between HMGA2 expression and chemosensitivity to 5-fluorour...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Xu, Xi, Wang, Yunfeng, Deng, Hong, Liu, Chungang, Wu, Jingjing, Lai, Maode
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839414/
https://ncbi.nlm.nih.gov/pubmed/29515783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24133
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