Differences in the Activity of Endogenous Bone Morphogenetic Protein Signaling Impact on the Ability of Induced Pluripotent Stem Cells to Differentiate to Corneal Epithelial‐Like Cells

Cornea is a clear outermost layer of the eye which enables transmission of light onto the retina. The transparent corneal epithelium is regenerated by limbal stem cells (LSCs), whose loss/dysfunction results in LSCs deficiency (LSCD). Ex vivo expansion of autologous LSCs obtained from patient's...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Kamarudin, Taty Anna, Bojic, Sanja, Collin, Joseph, Yu, Min, Alharthi, Sameer, Buck, Harley, Shortt, Alex, Armstrong, Lyle, Figueiredo, Francisco C., Lako, Majlinda
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839253/
https://ncbi.nlm.nih.gov/pubmed/29226476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2750
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