Functional, Antigen-Specific Stem Cell Memory (T(SCM)) CD4(+) T Cells Are Induced by Human Mycobacterium tuberculosis Infection

BACKGROUND: Maintenance of long-lasting immunity is thought to depend on stem cell memory T cells (T(SCM)), which have superior self-renewing capacity, longevity and proliferative potential compared with central memory (T(CM)) or effector (T(EFF)) T cells. Our knowledge of T(SCM) derives primarily f...

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Udgivet i:Front Immunol
Main Authors: Mpande, Cheleka A. M., Dintwe, One B., Musvosvi, Munyaradzi, Mabwe, Simbarashe, Bilek, Nicole, Hatherill, Mark, Nemes, Elisa, Scriba, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839236/
https://ncbi.nlm.nih.gov/pubmed/29545791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00324
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