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Mitigating the hook effect in lateral flow sandwich immunoassays using real-time reaction kinetics

The quantification of analyte concentrations using lateral flow assays is a low-cost and user-friendly alternative to traditional lab-based assays. However, sandwich-type immunoassays are often limited by the high-dose hook effect, which causes falsely low results when analytes are present in very h...

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Pubblicato in:Anal Chem
Autori principali: Rey, Elizabeth, O’Dell, Dakota, Mehta, Saurabh, Erickson, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839149/
https://ncbi.nlm.nih.gov/pubmed/28388030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b00638
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