Correlation between the results of in vitro and in vivo chromosomal damage tests in consideration of exposure levels of test chemicals

INTRODUCTION: We examined the correlation between the results of in vitro and in vivo chromosomal damage tests by using in-house data of 18 pharmaceutical candidates that showed positive results in the in vitro chromosomal aberration or micronucleus test using CHL/IU cells, and quantitatively analyz...

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Detalles Bibliográficos
Publicado en:Genes Environ
Main Authors: Yamamura, Eiji, Aruga, Chinami, Muto, Shigeharu, Baba, Nobuyuki, Uno, Yoshifumi
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
Assuntos:
Short Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838998/
https://ncbi.nlm.nih.gov/pubmed/29556374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-018-0094-3
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