A missense mutation in MYH1 is associated with susceptibility to immune-mediated myositis in Quarter Horses

BACKGROUND: The cause of immune-mediated myositis (IMM), characterized by recurrent, rapid-onset muscle atrophy in Quarter Horses (QH), is unknown. The histopathologic hallmark of IMM is lymphocytic infiltration of myofibers. The purpose of this study was to identify putative functional variants ass...

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Publicado en:Skelet Muscle
Main Authors: Finno, Carrie J., Gianino, Giuliana, Perumbakkam, Sudeep, Williams, Zoë J., Bordbari, Matthew H., Gardner, Keri L., Burns, Erin, Peng, Sichong, Durward-Akhurst, Sian A., Valberg, Stephanie J.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838957/
https://ncbi.nlm.nih.gov/pubmed/29510741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-018-0155-0
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