A population-based analysis of germline BRCA1 and BRCA2 testing among ovarian cancer patients in an era of histotype-specific approaches to ovarian cancer prevention

BACKGROUND: Identifying female carriers of BRCA1 and BRCA2 mutations is imperative for prevention of ovarian cancer and breast cancer. There are five major histologic subtypes of ovarian cancer and high grade serous cancer (the most common) is reported in 75–100% of BRCA1 and BRCA2 mutation carriers...

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Dades bibliogràfiques
Publicat a:BMC Cancer
Autors principals: Hanley, Gillian E., McAlpine, Jessica N., Miller, Dianne, Huntsman, David, Schrader, Kasmintan A., Blake Gilks, C., Mitchell, Gillian
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838948/
https://ncbi.nlm.nih.gov/pubmed/29506471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4153-8
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