Crosstalk between VEGFR and other receptor tyrosine kinases for TKI therapy of metastatic renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma (RCC), and is frequently accompanied by the genetic features of von Hippel–Lindau (VHL) loss. VHL loss increases the expression of hypoxia-inducible factors (HIFs) and their targets, including epidermal growth...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Principais autores: Lai, Yongchang, Zhao, Zhijian, Zeng, Tao, Liang, Xiongfa, Chen, Dong, Duan, Xiaolu, Zeng, Guohua, Wu, Wenqi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838927/
https://ncbi.nlm.nih.gov/pubmed/29527128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0530-2
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