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Studies on Prostaglandin-Endoperoxide Synthase 1: Lower Levels in Schizophrenia and After Treatment with Antipsychotic Drugs in Conjunction with Aspirin

BACKGROUND: Antipsychotic drugs plus aspirin (acetylsalicylic acid), which targets prostaglandin-endoperoxide synthase 1 (PTGS1: COX1), improved therapeutic outcomes when treating schizophrenia. Our microarray data showed higher levels of PTGS1 mRNA in the dorsolateral prefrontal cortex from subject...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Dean, Brian, Gibbons, Andrew, Gogos, Andrea, Udawela, Madhara, Thomas, Elizabeth, Scarr, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838806/
https://ncbi.nlm.nih.gov/pubmed/30052978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyx092
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