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Efficacy of Transdermal Estradiol and Micronized Progesterone in the Prevention of Depressive Symptoms in the Menopause Transition: A Randomized Clinical Trial

IMPORTANCE: The menopause transition and early postmenopausal period are associated with a 2- to 4-fold increased risk for clinically significant depressive symptoms. Although a few studies suggest that hormone therapy can effectively manage existing depression during this time, to our knowledge, th...

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Detalhes bibliográficos
Publicado no:JAMA Psychiatry
Main Authors: Gordon, Jennifer L., Rubinow, David R., Eisenlohr-Moul, Tory A., Xia, Kai, Schmidt, Peter J., Girdler, Susan S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838629/
https://ncbi.nlm.nih.gov/pubmed/29322164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2017.3998
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