Early Cognitive, Structural, and Microstructural Changes in Presymptomatic C9orf72 Carriers Younger Than 40 Years

IMPORTANCE: Presymptomatic carriers of chromosome 9 open reading frame 72 (C9orf72) mutation, the most frequent genetic cause of frontotemporal lobar degeneration and amyotrophic lateral sclerosis, represent the optimal target population for the development of disease-modifying drugs. Preclinical bi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Bertrand, Anne, Wen, Junhao, Rinaldi, Daisy, Houot, Marion, Sayah, Sabrina, Camuzat, Agnès, Fournier, Clémence, Fontanella, Sabrina, Routier, Alexandre, Couratier, Philippe, Pasquier, Florence, Habert, Marie-Odile, Hannequin, Didier, Martinaud, Olivier, Caroppo, Paola, Levy, Richard, Dubois, Bruno, Brice, Alexis, Durrleman, Stanley, Colliot, Olivier, Le Ber, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2017
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838615/
https://ncbi.nlm.nih.gov/pubmed/29197216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2017.4266
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados