Deep gray matter volume loss drives disability worsening in multiple sclerosis

OBJECTIVE: Gray matter (GM) atrophy occurs in all multiple sclerosis (MS) phenotypes. We investigated whether there is a spatiotemporal pattern of GM atrophy that is associated with faster disability accumulation in MS. METHODS: We analyzed 3,604 brain high‐resolution T1‐weighted magnetic resonance...

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Foilsithe in:Ann Neurol
Main Authors: Eshaghi, Arman, Prados, Ferran, Brownlee, Wallace J., Altmann, Daniel R., Tur, Carmen, Cardoso, M. Jorge, De Angelis, Floriana, van de Pavert, Steven H., Cawley, Niamh, De Stefano, Nicola, Stromillo, M. Laura, Battaglini, Marco, Ruggieri, Serena, Gasperini, Claudio, Filippi, Massimo, Rocca, Maria A., Rovira, Alex, Sastre‐Garriga, Jaume, Vrenken, Hugo, Leurs, Cyra E., Killestein, Joep, Pirpamer, Lukas, Enzinger, Christian, Ourselin, Sebastien, Wheeler‐Kingshott, Claudia A.M. Gandini, Chard, Declan, Thompson, Alan J., Alexander, Daniel C., Barkhof, Frederik, Ciccarelli, Olga
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2018
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Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838522/
https://ncbi.nlm.nih.gov/pubmed/29331092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25145
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