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LPS-primed CD11b(+) leukocytes serve as an effective carrier of Shiga toxin 2 to cause hemolytic uremic syndrome in mice

Shiga toxin (Stx)-induced hemolytic uremic syndrome (HUS) is a life-threatening complication associated with Stx-producing Escherichia coli infection. One critical barrier of understanding HUS is how Stx transports from infected intestine to kidney to cause HUS. Passive dissemination seems unlikely,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Niu, Shuo, Paluszynski, John, Bian, Zhen, Shi, Lei, Kidder, Koby, Liu, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838166/
https://ncbi.nlm.nih.gov/pubmed/29507316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22327-4
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