ロード中...

Lack of metabolism in (R)-ketamine’s antidepressant actions in a chronic social defeat stress model

Since the metabolism of (R,S)-ketamine to (2R,6R)-hydroxynorketamine (HNK) is reported to be essential for ketamine’s antidepressant effects, there is an increasing debate about antidepressant effects of (2R,6R)-HNK. Using pharmacokinetic and behavioral techniques, we investigated whether intracereb...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Zhang, Kai, Fujita, Yuko, Hashimoto, Kenji
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838158/
https://ncbi.nlm.nih.gov/pubmed/29507385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22449-9
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!