Strategies to assess and optimize stability of endogenous amines during cerebrospinal fluid sampling

INTRODUCTION: Metabolic profiling of cerebrospinal fluid (CSF) is a promising technique for studying brain diseases. Measurements should reflect the in vivo situation, so ex vivo metabolism should be avoided. OBJECTIVE: To investigate the effects of temperature (room temperature vs. 4 °C), centrifug...

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Publicado en:Metabolomics
Main Authors: Noga, Marek J., Zielman, Ronald, van Dongen, Robin M., Bos, Sabine, Harms, Amy, Terwindt, Gisela M., van den Maagdenberg, Arn M. J. M., Hankemeier, Thomas, Ferrari, Michel D.
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2018
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838118/
https://ncbi.nlm.nih.gov/pubmed/29527143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-018-1333-0
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