Development and characterization of an in vitro model for radiation-induced fibrosis

Radiation-induced fibrosis (RIF) is a major side effect of radiotherapy in cancer patients with no effective therapeutic options. RIF involves excess deposition and aberrant remodeling of the extracellular matrix (ECM) leading to stiffness in tissues and organ failure. Development of preclinical mod...

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Pubblicato in:Radiat Res
Autori principali: Kumar, Dhruv, Yalamanchali, Sreeya, New, Jacob, Parsel, Sean, New, Natalie, Holcomb, Andrew, Gunewardena, Sumedha, Tawfik, Ossama, Lominska, Chris, Kimler, Bruce F., Anant, Shrikant, Kakarala, Kiran, Tsue, Terance T, Shnayder, Yelizaveta, Sykes, Kevin, Padhye, Subhash, Thomas, Sufi Mary
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837959/
https://ncbi.nlm.nih.gov/pubmed/29351058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR14926.1
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