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Allosteric effector ppGpp potentiates the inhibition of transcript initiation by DksA
DksA and ppGpp are the central players in the stringent response and mediate a complete reprogramming of the transcriptome. A major component of the response is a reduction in ribosome synthesis, which is accomplished by the synergistic action of DksA and ppGpp bound to RNA polymerase (RNAP) inhibit...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5837818/ https://ncbi.nlm.nih.gov/pubmed/29478808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.035 |
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