Using computer assisted image analysis to determine the optimal Ki67 threshold for predicting outcome of invasive breast cancer

BACKGROUND: Ki67 positivity in invasive breast cancers has an inverse correlation with survival outcomes and serves as an immunohistochemical surrogate for molecular subtyping of breast cancer, particularly ER positive breast cancer. The optimal threshold of Ki67 in both settings, however, remains e...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tay, Timothy Kwang Yong, Thike, Aye Aye, Pathmanathan, Nirmala, Jara-Lazaro, Ana Richelia, Iqbal, Jabed, Sng, Adeline Shi Hui, Ye, Heng Seow, Lim, Jeffrey Chun Tatt, Koh, Valerie Cui Yun, Tan, Jane Sie Yong, Yeong, Joe Poh Sheng, Chow, Zi Long, Li, Hui Hua, Cheng, Chee Leong, Tan, Puay Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837769/
https://ncbi.nlm.nih.gov/pubmed/29545924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24398
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