Profound deficits in hippocampal synaptic plasticity after traumatic brain injury and seizure is ameliorated by prophylactic levetiracetam

AIM: To determine the precise effects of post-traumatic seizure activity on hippocampal processes, we induced seizures at various intervals after traumatic brain injury (TBI) and analyzed plasticity at CA1 Schaffer collateral synapses. MATERIAL AND METHODS: Rats were initially separated into two gro...

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Vydáno v:Oncotarget
Hlavní autoři: Chen, Yuan-Hao, Kuo, Tung-Tai, Yi-Kung Huang, Eagle, Hoffer, Barry J., Chou, Yu-Ching, Chiang, Yung-Hsiao, Ma, Hsin-I, Miller, Jonathan P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837755/
https://ncbi.nlm.nih.gov/pubmed/29545916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23923
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