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Brd4 regulates the expression of essential autophagy genes and Keap1 in AML cells

We have recently reported that activation of Brd4 is associated with the presence of autophagy in NPMc+ and MLL AML cells. In order to determine the mechanisms underlying this relationship, we have examined the role of Brd4 in regulating the expression of several genes that are central to the proces...

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Pubblicato in:Oncotarget
Autori principali: Huang, Min, Zhu, Li, Garcia, Jacqueline S., Li, Michael X., Gentles, Andrew J., Mitchell, Beverly S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837743/
https://ncbi.nlm.nih.gov/pubmed/29545928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24432
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