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Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies

Background: Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults. Previous genome-wide association studies (GWAS) of 300 000 genotyped variants identified MN-associated loci at HLA-DQA1 and PLA2R1. Methods: We used a combined approach of genotype imputation, GWAS, human leuc...

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Detalhes bibliográficos
Publicado no:Nephrol Dial Transplant
Main Authors: Sekula, Peggy, Li, Yong, Stanescu, Horia C., Wuttke, Matthias, Ekici, Arif B., Bockenhauer, Detlef, Walz, Gerd, Powis, Stephen H., Kielstein, Jan T., Brenchley, Paul, Eckardt, Kai-Uwe, Kronenberg, Florian, Kleta, Robert, Köttgen, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837679/
https://ncbi.nlm.nih.gov/pubmed/27333618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfw001
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