Minocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration

Survivors of a traumatic brain injury can deteriorate years later, developing brain atrophy and dementia. Traumatic brain injury triggers chronic microglial activation, but it is unclear whether this is harmful or beneficial. A successful chronic-phase treatment for traumatic brain injury might be t...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Scott, Gregory, Zetterberg, Henrik, Jolly, Amy, Cole, James H, De Simoni, Sara, Jenkins, Peter O, Feeney, Claire, Owen, David R, Lingford-Hughes, Anne, Howes, Oliver, Patel, Maneesh C, Goldstone, Anthony P, Gunn, Roger N, Blennow, Kaj, Matthews, Paul M, Sharp, David J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837493/
https://ncbi.nlm.nih.gov/pubmed/29272357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awx339
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