Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials

AIMS: Recent guidelines recommend that patients with heart failure and left ventricular ejection fraction (LVEF) 40–49% should be managed similar to LVEF ≥ 50%. We investigated the effect of beta-blockers according to LVEF in double-blind, randomized, placebo-controlled trials. METHODS AND RESULTS:...

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Bibliographic Details
Published in:Eur Heart J
Main Authors: Cleland, John G F, Bunting, Karina V, Flather, Marcus D, Altman, Douglas G, Holmes, Jane, Coats, Andrew J S, Manzano, Luis, McMurray, John J V, Ruschitzka, Frank, van Veldhuisen, Dirk J, von Lueder, Thomas G, Böhm, Michael, Andersson, Bert, Kjekshus, John, Packer, Milton, Rigby, Alan S, Rosano, Giuseppe, Wedel, Hans, Hjalmarson, Åke, Wikstrand, John, Kotecha, Dipak
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Fast Track Clinical Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837435/
https://ncbi.nlm.nih.gov/pubmed/29040525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehx564
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