Prognostic enrichment design in clinical trials for autosomal dominant polycystic kidney disease: the HALT-PKD clinical trial

BACKGROUND: Patients with mild autosomal dominant polycystic kidney disease (ADPKD) are less likely to be informative in randomized clinical trials (RCTs). We previously developed an imaging classification of ADPKD (typical diffuse cyst distribution Class 1A–E and atypical cyst distribution Class 2)...

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Detalhes bibliográficos
Publicado no:Nephrol Dial Transplant
Main Authors: Irazabal, María V, Abebe, Kaleab Z, Bae, Kyongtae Ty, Perrone, Ronald D, Chapman, Arlene B, Schrier, Robert W, Yu, Alan S, Braun, William E, Steinman, Theodore I, Harris, Peter C, Flessner, Michael F, Torres, Vicente E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837227/
https://ncbi.nlm.nih.gov/pubmed/27484667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfw294
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