Prognostic enrichment design in clinical trials for autosomal dominant polycystic kidney disease: the HALT-PKD clinical trial

BACKGROUND: Patients with mild autosomal dominant polycystic kidney disease (ADPKD) are less likely to be informative in randomized clinical trials (RCTs). We previously developed an imaging classification of ADPKD (typical diffuse cyst distribution Class 1A–E and atypical cyst distribution Class 2)...

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Bibliografiska uppgifter
I publikationen:Nephrol Dial Transplant
Huvudupphovsmän: Irazabal, María V, Abebe, Kaleab Z, Bae, Kyongtae Ty, Perrone, Ronald D, Chapman, Arlene B, Schrier, Robert W, Yu, Alan S, Braun, William E, Steinman, Theodore I, Harris, Peter C, Flessner, Michael F, Torres, Vicente E
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2017
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837227/
https://ncbi.nlm.nih.gov/pubmed/27484667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfw294
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