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A dual component heme biosensor that integrates heme transport and synthesis in bacteria

Bacterial pathogens acquire host iron to power cellular processes and replication. Heme, an iron-containing co-factor bound to hemoglobin, is scavenged by bacterial proteins to attain iron. Methods to measure intracellular heme are laborious, involve complex chemistry, or require radioactivity. Such...

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Detalles Bibliográficos
Publicado en:J Microbiol Methods
Autores principales: Nobles, Christopher L., Clark, Justin R., Green, Sabrina I., Maresso, Anthony W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837058/
https://ncbi.nlm.nih.gov/pubmed/26253803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mimet.2015.07.011
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