Pharmacokinetics of concentrated naloxone nasal spray for opioid overdose reversal: Phase I healthy volunteer study

BACKGROUND AND AIMS: Take‐home naloxone can prevent death from heroin/opioid overdose, but pre‐provision is difficult because naloxone is usually given by injection. Non‐injectable alternatives, including naloxone nasal sprays, are currently being developed. To be effective, the intranasal (i.n.) sp...

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Detalhes bibliográficos
Publicado no:Addiction
Main Authors: McDonald, Rebecca, Lorch, Ulrike, Woodward, Jo, Bosse, Björn, Dooner, Helen, Mundin, Gill, Smith, Kevin, Strang, John
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836974/
https://ncbi.nlm.nih.gov/pubmed/29143400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/add.14033
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