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Effects of common cold and concomitant administration of nasal decongestant on the pharmacokinetics and pharmacodynamics of nasal glucagon in otherwise healthy participants: A randomized clinical trial

AIMS: Nasal glucagon (NG) is a nasally‐administered glucagon powder, absorbed through the nasal mucosa, designed for treatment of severe hypoglycaemia. This study evaluated the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of NG in otherwise healthy participants with common colds and after...

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Publicat a:Diabetes Obes Metab
Autors principals: Guzman, Cristina B., Dulude, Helene, Piché, Claude, Rufiange, Marianne, Sadoune, Aziz A., Rampakakis, Emmanouil, Carballo, Dolores, Triest, Myriam, Zhang, Michelle Xiaotian, Zhang, Shuyu, Tafreshi, Maryam, Sicard, Eric
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836949/
https://ncbi.nlm.nih.gov/pubmed/29053231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.13134
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