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Problems in anticoagulation of a patient with antibiotic treatment for endocarditis: interaction of rifampicin and vitamin K antagonists

The cytochrome P450 is a superfamily of isoenzymes that are responsible for the metabolism of many drugs. Significant changes in pharmacokinetics and drug interactions may be due to induction of hepatic cytochrome P450 enzymes. Rifampicin is a common inducer of CYP3A4. We report a case of a 57-year-...

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Bibliografiske detaljer
Udgivet i:BMJ Case Rep
Main Authors: Mizera, Lars, Geisler, Tobias, Mörike, Klaus, Gawaz, Meinrad, Steeg, Martin
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836613/
https://ncbi.nlm.nih.gov/pubmed/29440136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr-2016-215155
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