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Problems in anticoagulation of a patient with antibiotic treatment for endocarditis: interaction of rifampicin and vitamin K antagonists

The cytochrome P450 is a superfamily of isoenzymes that are responsible for the metabolism of many drugs. Significant changes in pharmacokinetics and drug interactions may be due to induction of hepatic cytochrome P450 enzymes. Rifampicin is a common inducer of CYP3A4. We report a case of a 57-year-...

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Detalhes bibliográficos
Publicado no:BMJ Case Rep
Main Authors: Mizera, Lars, Geisler, Tobias, Mörike, Klaus, Gawaz, Meinrad, Steeg, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836613/
https://ncbi.nlm.nih.gov/pubmed/29440136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr-2016-215155
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