Intravenous injection of beta-amyloid seeds promotes cerebral amyloid angiopathy (CAA)

Seeding and spread of beta-amyloid (Aβ) pathologies have been considered to be based on prion-like mechanisms. However, limited transmissibility of Aβ seeding activity upon peripheral exposure would represent a key difference to prions, not only in terms of pathogenesis but also in terms of potentia...

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Bibliographic Details
Published in:Acta Neuropathol Commun
Main Authors: Burwinkel, Michael, Lutzenberger, Manuel, Heppner, Frank L., Schulz-Schaeffer, Walter, Baier, Michael
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836327/
https://ncbi.nlm.nih.gov/pubmed/29506560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0511-7
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