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A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat

Heterocyclic amines (HCAs) produced during high-temperature cooking have been studied extensively in terms of their genotoxic/genetic effects, but recent work has implicated epigenetic mechanisms involving non-coding RNAs. Colon tumors induced in the rat by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyr...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Chen, Ying-Shiuan, Wang, Rong, Dashwood, Wan-Mohaiza, Löhr, Christiane V., Williams, David E., Ho, Emily, Mertens-Talcott, Susanne, Dashwood, Roderick H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836314/
https://ncbi.nlm.nih.gov/pubmed/28289824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-1945-6
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