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The phospholipid-repair system LplT/Aas in Gram-negative bacteria protects the bacterial membrane envelope from host phospholipase A(2) attack
Secretory phospholipases A(2) (sPLA(2)s) are potent components of mammalian innate-immunity antibacterial mechanisms. sPLA(2) enzymes attack bacteria by hydrolyzing bacterial membrane phospholipids, causing membrane disorganization and cell lysis. However, most Gram-negative bacteria are naturally r...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5836115/ https://ncbi.nlm.nih.gov/pubmed/29348168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001231 |
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