Bioapplications of Cell-SELEX-Generated Aptamers in Cancer Diagnostics, Therapeutics, Theranostics and Biomarker Discovery: A Comprehensive Review

Currently, functional single-stranded oligonucleotide probes, termed aptamers, generated by an iterative technology, Systematic Evolution of Ligands by Exponential Enrichment (SELEX), are utilized to selectively target molecules or cells with high affinity. Aptamers hold considerable promise as mult...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Pang, Xuehui, Cui, Cheng, Wan, Shuo, Jiang, Ying, Zhang, Liangliang, Xia, Lian, Li, Long, Li, Xiaowei, Tan, Weihong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836079/
https://ncbi.nlm.nih.gov/pubmed/29425173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10020047
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