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MYC Regulates α6 Integrin Subunit Expression and Splicing Under Its Pro-Proliferative ITGA6A Form in Colorectal Cancer Cells

The α6 integrin subunit (ITGA6) pre-mRNA undergoes alternative splicing to form two splicing variants, named ITGA6A and ITGA6B. In primary human colorectal cancer cells, the levels of both ITGA6 and β4 integrin subunit (ITGB4) subunits of the α6β4 integrin are increased. We previously found that the...

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Dades bibliogràfiques
Publicat a:Cancers (Basel)
Autors principals: Groulx, Jean-François, Boudjadi, Salah, Beaulieu, Jean-François
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836074/
https://ncbi.nlm.nih.gov/pubmed/29401653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10020042
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