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A Cytoplasmic Antiholin Is Embedded In Frame with the Holin in a Lactobacillus fermentum Bacteriophage

In double-stranded DNA bacteriophages, infection cycles are ended by host cell lysis through the action of phage-encoded endolysins and holins. The precise timing of lysis is regulated by the holin inhibitors, named antiholins. Sequence analysis has revealed that holins with a single transmembrane d...

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Veröffentlicht in:Appl Environ Microbiol
Hauptverfasser: Guo, Tingting, Xin, Yongping, Zhang, Chenchen, Kong, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835725/
https://ncbi.nlm.nih.gov/pubmed/29305511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02518-17
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