Small cell lung cancer tumors and preclinical models display heterogeneity of neuroendocrine phenotypes

BACKGROUND: Small cell lung cancer (SCLC) is a deadly, high grade neuroendocrine (NE) tumor without recognized morphologic heterogeneity. However, over 30 years ago we described a SCLC subtype with “variant” morphology which did not express some NE markers and exhibited more aggressive growth. METHO...

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Detalhes bibliográficos
Publicado no:Transl Lung Cancer Res
Main Authors: Zhang, Wei, Girard, Luc, Zhang, Yu-An, Haruki, Tomohiro, Papari-Zareei, Mahboubeh, Stastny, Victor, Ghayee, Hans K., Pacak, Karel, Oliver, Trudy G., Minna, John D., Gazdar, Adi F.
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2018
Assuntos:
Original Article on Small Cell Lung Cancer: New Models, Markers and Beyond
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835590/
https://ncbi.nlm.nih.gov/pubmed/29535911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2018.02.02
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