6-Gingerol Regulates Hepatic Cholesterol Metabolism by Up-regulation of LDLR and Cholesterol Efflux-Related Genes in HepG2 Cells

Gingerols, the pungent ingredients in ginger, are reported to possess a cholesterol-lowering activity. However, the underlying mechanism remains unclear. The present study was to investigate how 6-gingerol (6-GN), the most abundant gingerol in fresh ginger, regulates hepatic cholesterol metabolism....

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Vydáno v:Front Pharmacol
Hlavní autoři: Li, Xiao, Guo, Jingting, Liang, Ning, Jiang, Xinwei, Song, Yuan, Ou, Shiyi, Hu, Yunfeng, Jiao, Rui, Bai, Weibin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835308/
https://ncbi.nlm.nih.gov/pubmed/29535632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00159
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