Liver X Receptor Inverse Agonist SR9243 Suppresses Nonalcoholic Steatohepatitis Intrahepatic Inflammation and Fibrosis

Abnormal metabolism of cholesterol may be a contributing factor in nonalcoholic steatohepatitis (NASH) pathogenesis. Accumulating evidence has shown that liver X receptor (LXR) is closely related to intrahepatic inflammation and fibrosis. In this study, we evaluated the effects of a novel liver-spec...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Huang, Peng, Kaluba, Benson, Jiang, Xiao-lin, Chang, Shi, Tang, Xiao-feng, Mao, Lin-feng, Zhang, Zhi-peng, Huang, Fei-zhou
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835296/
https://ncbi.nlm.nih.gov/pubmed/29670908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8071093
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