Metabolic Heterogeneity Evidenced by MRS among Patient-Derived Glioblastoma Multiforme Stem-Like Cells Accounts for Cell Clustering and Different Responses to Drugs

Clustering of patient-derived glioma stem-like cells (GSCs) through unsupervised analysis of metabolites detected by magnetic resonance spectroscopy (MRS) evidenced three subgroups, namely clusters 1a and 1b, with high intergroup similarity and neural fingerprints, and cluster 2, with a metabolism t...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Grande, Sveva, Palma, Alessandra, Ricci-Vitiani, Lucia, Luciani, Anna Maria, Buccarelli, Mariachiara, Biffoni, Mauro, Molinari, Agnese, Calcabrini, Annarica, D'Amore, Emanuela, Guidoni, Laura, Pallini, Roberto, Viti, Vincenza, Rosi, Antonella
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835274/
https://ncbi.nlm.nih.gov/pubmed/29531533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3292704
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