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Population-dependent Intron Retention and DNA Methylation in Breast Cancer

Regulation of gene expression by DNA methylation in gene promoter regions is well-studied; however, the effects of methylation in the gene body (exons and introns) on gene expression are comparatively understudied. Recently, hyper-methylation has been implicated in the inclusion of alternatively spl...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Kim, Dongwook, Shivakumar, Manu, Han, Seonggyun, Sinclair, Michael S, Lee, Young-ji, Zheng, Yonglan, Olopade, Olufunmilayo I, Kim, Dokyoon, Lee, Younghee
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835176/
https://ncbi.nlm.nih.gov/pubmed/29330282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0227
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