Chimeric Antigen Receptor-Engineered Human Gamma Delta T Cells: Enhanced Cytotoxicity with Retention of Cross Presentation

Gamma delta T (γδT) lymphocytes are primed for rapid function, including cytotoxicity toward cancer cells, and are a component of the immediate stress response. Following activation, they can function as professional antigen-presenting cells. Chimeric antigen receptors (CARs) work by focusing T cell...

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Pubblicato in:Mol Ther
Autori principali: Capsomidis, Anna, Benthall, Gabriel, Van Acker, Heleen H., Fisher, Jonathan, Kramer, Anne M., Abeln, Zarah, Majani, Yvonne, Gileadi, Talia, Wallace, Rebecca, Gustafsson, Kenth, Flutter, Barry, Anderson, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2018
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835118/
https://ncbi.nlm.nih.gov/pubmed/29310916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.12.001
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