Updated and standardized genome-scale reconstruction of Mycobacterium tuberculosis H37Rv, iEK1011, simulates flux states indicative of physiological conditions

BACKGROUND: The efficacy of antibiotics against M. tuberculosis has been shown to be influenced by experimental media conditions. Investigations of M. tuberculosis growth in physiological conditions have described an environment that is different from common in vitro media. Thus, elucidating the int...

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Bibliografske podrobnosti
izdano v:BMC Syst Biol
Main Authors: Kavvas, Erol S., Seif, Yara, Yurkovich, James T., Norsigian, Charles, Poudel, Saugat, Greenwald, William W., Ghatak, Sankha, Palsson, Bernhard O., Monk, Jonathan M.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834885/
https://ncbi.nlm.nih.gov/pubmed/29499714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0557-y
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