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Drug resistance in anaplastic lymphoma kinase‐rearranged lung cancer

The anaplastic lymphoma kinase (ALK) gene encodes a receptor tyrosine kinase, and many kinds of ALK fusion genes have been found in a variety of carcinomas. There is almost no detectable expression of ALK in adults. However, through ALK gene rearrangement, the resultant ALK fusion protein is aberran...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Sci
1. Verfasser: Katayama, Ryohei
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834792/
https://ncbi.nlm.nih.gov/pubmed/29336091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13504
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