Interacting-heads motif has been conserved as a mechanism of myosin II inhibition since before the origin of animals

Electron microscope studies have shown that the switched-off state of myosin II in muscle involves intramolecular interaction between the two heads of myosin and between one head and the tail. The interaction, seen in both myosin filaments and isolated molecules, inhibits activity by blocking actin-...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Lee, Kyoung Hwan, Sulbarán, Guidenn, Yang, Shixin, Mun, Ji Young, Alamo, Lorenzo, Pinto, Antonio, Sato, Osamu, Ikebe, Mitsuo, Liu, Xiong, Korn, Edward D., Sarsoza, Floyd, Bernstein, Sanford I., Padrón, Raúl, Craig, Roger
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2018
主題:
PNAS Plus
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834683/
https://ncbi.nlm.nih.gov/pubmed/29444861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715247115
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