Interacting-heads motif has been conserved as a mechanism of myosin II inhibition since before the origin of animals

Electron microscope studies have shown that the switched-off state of myosin II in muscle involves intramolecular interaction between the two heads of myosin and between one head and the tail. The interaction, seen in both myosin filaments and isolated molecules, inhibits activity by blocking actin-...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Lee, Kyoung Hwan, Sulbarán, Guidenn, Yang, Shixin, Mun, Ji Young, Alamo, Lorenzo, Pinto, Antonio, Sato, Osamu, Ikebe, Mitsuo, Liu, Xiong, Korn, Edward D., Sarsoza, Floyd, Bernstein, Sanford I., Padrón, Raúl, Craig, Roger
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834683/
https://ncbi.nlm.nih.gov/pubmed/29444861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715247115
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