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Significance of risk polymorphisms for depression depends on stress exposure

Depression is a polygenic and multifactorial disorder where environmental effects exert a significant impact, yet most genetic studies do not consider the effect of stressors which may be one reason for the lack of replicable results in candidate gene studies, GWAS and between human studies and anim...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Gonda, Xenia, Hullam, Gabor, Antal, Peter, Eszlari, Nora, Petschner, Peter, Hökfelt, Tomas GM, Anderson, Ian Muir, Deakin, John Francis William, Juhasz, Gabriella, Bagdy, Gyorgy
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834495/
https://ncbi.nlm.nih.gov/pubmed/29500446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22221-z
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