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mRNA Translation Gone Awry: Translation Fidelity and Neurological Disease
Errors during mRNA translation can lead to a reduction in the levels of functional proteins and an increase in deleterious molecules. Advances in next-generation sequencing have led to the discovery of rare genetic disorders, many caused by mutations in genes encoding the mRNA translation machinery,...
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| Publicado no: | Trends Genet |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5834357/ https://ncbi.nlm.nih.gov/pubmed/29352613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2017.12.007 |
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