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MGMT promoter methylation in Peruvian patients with glioblastoma

PURPOSE: O(6)-methylguanine–DNA methyltransferase (MGMT) promoter methylation predicts the outcome and response to alkylating chemotherapy in glioblastoma. The aim of this study is to evaluate the prevalence of MGMT methylation in Peruvian glioblastoma cases. PATIENTS AND METHODS: We evaluated retro...

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Publicado en:Ecancermedicalscience
Autores principales: Belmar-Lopez, Carolina, Castaneda, Carlos A, Castillo, Miluska, García-Corrochano, Pamela, Orrego, Enrique, Meléndez, Barbara, Casavilca, Sandro, Flores, Claudio
Formato: Artigo
Lenguaje:Inglês
Publicado: Cancer Intelligence 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834313/
https://ncbi.nlm.nih.gov/pubmed/29515653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3332/ecancer.2018.812
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