Interstitial near-infrared photoimmunotherapy: effective treatment areas and light doses needed for use with fiber optic diffusers

Near-infrared photoimmunotherapy (NIR-PIT), a promising cancer therapy utilizing an antibody-photoabsorber conjugate (APC) and NIR light, which induces rapid necrotic cell death only in APC-bound cells. Effective NIR-PIT in mouse models has been achieved using superficial light illumination (SLI) wi...

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Vydáno v:Oncotarget
Hlavní autoři: Okuyama, Shuhei, Nagaya, Tadanobu, Sato, Kazuhide, Ogata, Fusa, Maruoka, Yasuhiro, Choyke, Peter L., Kobayashi, Hisataka
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834257/
https://ncbi.nlm.nih.gov/pubmed/29541404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24329
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