Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naïve B cells, and facilitates recruitment of transcription factors to the viral genome

The Epstein-Barr virus (EBV) nuclear antigen leader protein (EBNA-LP) is the first viral latency-associated protein produced after EBV infection of resting B cells. Its role in B cell transformation is poorly defined, but it has been reported to enhance gene activation by the EBV protein EBNA2 in vi...

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Pubblicato in:PLoS Pathog
Autori principali: Szymula, Agnieszka, Palermo, Richard D., Bayoumy, Amr, Groves, Ian J., Ba abdullah, Mohammed, Holder, Beth, White, Robert E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834210/
https://ncbi.nlm.nih.gov/pubmed/29462212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006890
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