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Statistical controversies in clinical research: basket trials, umbrella trials, and other master protocols: a review and examples
In recent years, cancers once viewed as relatively homogeneous in terms of organ location and treatment strategy are now better understood to be increasingly heterogeneous across biomarker and genetically defined patient subgroups. This has produced a shift toward development of biomarker-targeted a...
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| Publicado no: | Ann Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5834138/ https://ncbi.nlm.nih.gov/pubmed/28177494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdw413 |
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